Pathway macrostates

Mammalian Cell Signaling Pathway Macrostates: discrete, named, experimentally interpretable operating regimes

The table below catalogs major mammalian signaling pathways by their experimentally observable macrostate(s) — the coarse-grained, discrete operating regimes that go beyond simple “pathway is on/off” and are distinguished by measurable dynamical signatures. For each, I describe the recognizable states and the experimental readout used to discriminate them.

Summary Table of Discrete Signaling Macrostates