https://www.dwarkesh.com/p/jacob-kimmel

Transcript:

Timestamps

(00:00:00) – Three reasons evolution didn’t optimize for longevity

(00:12:07) – Why didn’t humans evolve their own antibiotics?

(00:25:26) – De-aging cells via epigenetic reprogramming

(00:44:43) – Viral vectors and other delivery mechanisms

(01:06:22) – Synthetic transcription factors

(01:09:31) – Can virtual cells break Eroom’s Law?

(01:31:32) – Economic models for pharma

Transcript

00:00:00 – Three reasons evolution didn’t optimize for longevity

Dwarkesh Patel 00:00:00

Today I have the pleasure of interviewing Jacob Kimmel, who is the president and co-founder of NewLimit, where they’re trying to epigenetically reprogram cells to their younger states.

Jacob, thanks so much for coming on the podcast.

Jacob Kimmel 00:00:09

Thanks so much for having me. Looking forward to the conversation.

Dwarkesh Patel 00:00:11

All right,