BAK (BAK1)
What it is. Pro-apoptotic partner of BAX; forms pores in mitochondria to trigger cell suicide.
Why it matters here. Loss impairs apoptosis; tumors often tilt the balance toward survival.
Notes. Type: BCL-2 family effector.
What it is. Pro-apoptotic partner of BAX; forms pores in mitochondria to trigger cell suicide.
Why it matters here. Loss impairs apoptosis; tumors often tilt the balance toward survival.
Notes. Type: BCL-2 family effector.