GAPDH

What it is. Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively (PubMed:11724794, PubMed:3170585).

Why it matters here. Inflammatory signaling component that affects aging and age-related disease.

Notes. Type: receptor; Pathways: Gluconeogenesis, Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5, Glycolysis.