p21^CIP1 (CDKN1A)
What it is. p53-induced inhibitor of multiple cyclin–CDK complexes.
Why it matters here. Implements p53-mediated cell-cycle arrest; contributes to senescence entry.
Notes. Type: CKI; Upstream: p53.
What it is. p53-induced inhibitor of multiple cyclin–CDK complexes.
Why it matters here. Implements p53-mediated cell-cycle arrest; contributes to senescence entry.
Notes. Type: CKI; Upstream: p53.
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