PIK3CA (PIK3CA)
What it is. Catalytic subunit of class I PI3K that generates PIP3 to recruit AKT.
Why it matters here. Activating mutations increase survival and growth signaling.
Notes. Partners: PTEN (antagonist), AKT.
What it is. Catalytic subunit of class I PI3K that generates PIP3 to recruit AKT.
Why it matters here. Activating mutations increase survival and growth signaling.
Notes. Partners: PTEN (antagonist), AKT.
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