PIK3CA (PIK3CA)
What it is. Catalytic subunit of class I PI3K that generates PIP3 to recruit AKT.
Why it matters here. Activating mutations increase survival and growth signaling.
Notes. Partners: PTEN (antagonist), AKT.
- content(78)
- wiki(73)
- AKT1
- AKT2 (AKT2)
- Antagonistic Pleiotropy Theory
- APAF1
- ARF (p14^ARF)
- ATM
- ATR
- BAK (BAK1)
- BAX
- BCL‑2
- BCL‑XL (BCL2L1)
- beta-catenin (CTNNB1)
- BRAF (BRAF)
- Caspase-3 (CASP3)
- Cellular Senescence
- CTLA-4 (CTLA4)
- CTVT - Canine Transmissible Venereal Tumor
- De-Darwinization
- Death Pact
- Disposable Soma Theory
- DNMT1
- E2F1 (E2F1)
- EGF (EGF)
- EGFR (ERBB1)
- FAS (CD95)
- Fibrinogen alpha chain (FGA)
- FOXO3 (FOXO3)
- GAPDH
- Glossary
- HLA-A (HLA-A)
- IGF-1
- IL-10
- IL-6
- IL-8 (CXCL8)
- Insulin
- JAK2
- KRAS (KRAS)
- Lewontin's conditions
- LMNA
- MAP2K1 (MEK1)
- MCL-1
- MDM2
- MMP9 (MMP9)
- MTOR (MTOR)
- MYC
- NFE2L2 (NRF2)
- NOTCH1 (NOTCH1)
- OGG1
- p16^INK4a (CDKN2A)
- p21^CIP1 (CDKN1A)
- p53 (TP53)
- PD-1 (PDCD1)
- PD-L1 (CD274)
- PIK3CA (PIK3CA)
- PRKAA1 (AMPKα1)
- QSOX1
- Rb (RB1)
- Selection Shadow Theory
- Self-Fertilization
- SIRT1 (SIRT1)
- Sonic hedgehog (SHH)
- TAZ (WWTR1)
- Telomerase (TERT)
- Telomeres
- TGF-beta 1 (TGFB1)
- TNF (TNF)
- Tumor Suppressor Theory of Aging
- UBE3A
- VEGF (VEGFA)
- WNT3A (WNT3A)
- XIAP
- YAP (YAP1)
- ZEB1
- post(3)
- apps(2)
- protein(61)
- AKT1
- AKT2 (AKT2)
- APAF1
- ARF (p14^ARF)
- ATM
- ATR
- BAK (BAK1)
- BAX
- BCL‑2
- BCL‑XL (BCL2L1)
- beta-catenin (CTNNB1)
- BRAF (BRAF)
- Caspase-3 (CASP3)
- CTLA-4 (CTLA4)
- DNMT1
- E2F1 (E2F1)
- EGF (EGF)
- EGFR (ERBB1)
- FAS (CD95)
- Fibrinogen alpha chain (FGA)
- FOXO3 (FOXO3)
- GAPDH
- HLA-A (HLA-A)
- IGF-1
- IL-10
- IL-6
- IL-8 (CXCL8)
- Insulin
- JAK2
- KRAS (KRAS)
- LMNA
- MAP2K1 (MEK1)
- MCL-1
- MDM2
- MMP9 (MMP9)
- MTOR (MTOR)
- MYC
- NFE2L2 (NRF2)
- NOTCH1 (NOTCH1)
- OGG1
- p16^INK4a (CDKN2A)
- p21^CIP1 (CDKN1A)
- p53 (TP53)
- PD-1 (PDCD1)
- PD-L1 (CD274)
- PIK3CA (PIK3CA)
- PRKAA1 (AMPKα1)
- QSOX1
- Rb (RB1)
- SIRT1 (SIRT1)
- Sonic hedgehog (SHH)
- TAZ (WWTR1)
- Telomerase (TERT)
- TGF-beta 1 (TGFB1)
- TNF (TNF)
- UBE3A
- VEGF (VEGFA)
- WNT3A (WNT3A)
- XIAP
- YAP (YAP1)
- ZEB1
- meta(1)
- untagged(8)
PIK3CA
PIK3CA
Molecular→Persona
Mass124 kDa
→Height124 cm
TransmembraneNo
→GenderFemale
Membrane Depth1
→Settingoutdoors
Classificationoncogene
→Politicspro-Growth
First LetterP
→Skin Hue🅿
RVIS9
→Skin Lightness9%
Tissue Specificity23
→Skin Saturation23%
kegg_familiesMembrane trafficking
→AestheticsCargopunk
Disorder15%
→Age15