KRAS (KRAS)
What it is. Molecular switch downstream of many growth factor receptors.
Why it matters here. Locked‑on RAS drives mitogen‑independent growth and can trigger senescence tripwires.
Notes. Pathway: RAS–RAF–MEK–ERK.
What it is. Molecular switch downstream of many growth factor receptors.
Why it matters here. Locked‑on RAS drives mitogen‑independent growth and can trigger senescence tripwires.
Notes. Pathway: RAS–RAF–MEK–ERK.
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