PD-1 (PDCD1)
What it is. Receptor on T cells that, when engaged by PD‑L1, reduces T‑cell activity.
Why it matters here. Target of checkpoint blockade therapies to restore anti‑tumor immunity.
Notes. Ligand: PD‑L1; Therapy: anti‑PD‑1 antibodies.
What it is. Receptor on T cells that, when engaged by PD‑L1, reduces T‑cell activity.
Why it matters here. Target of checkpoint blockade therapies to restore anti‑tumor immunity.
Notes. Ligand: PD‑L1; Therapy: anti‑PD‑1 antibodies.