PD-L1 (CD274)
What it is. Immune “brake” ligand displayed on cells to dampen T‑cell attack.
Why it matters here. Tumors upregulate PD‑L1 to evade immune surveillance.
Notes. Receptor: PD‑1 on T cells; Therapy: anti‑PD‑1/PD‑L1 antibodies.
What it is. Immune “brake” ligand displayed on cells to dampen T‑cell attack.
Why it matters here. Tumors upregulate PD‑L1 to evade immune surveillance.
Notes. Receptor: PD‑1 on T cells; Therapy: anti‑PD‑1/PD‑L1 antibodies.